Sphingomyelin phosphodiesterase, C-terminal domain
Short name | ASM_C |
Description
References
1.Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease. Zhou YF, Metcalf MC, Garman SC, Edmunds T, Qiu H, Wei RR. Nat Commun 7, 13082, (2016). View articlePMID: 27725636
2.Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2. Oninla VO, Breiden B, Babalola JO, Sandhoff K. J Lipid Res 55, 2606-19, (2014). PMID: 25339683
3.Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair. Tam C, Idone V, Devlin C, Fernandes MC, Flannery A, He X, Schuchman E, Tabas I, Andrews NW. J Cell Biol 189, 1027-38, (2010). PMID: 20530211
4.Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency. Acuna M, Castro-Fernandez V, Latorre M, Castro J, Schuchman EH, Guixe V, Gonzalez M, Zanlungo S. Biochem Biophys Res Commun 479, 496-501, (2016). PMID: 27659707
5.Crystal structure of mammalian acid sphingomyelinase. Gorelik A, Illes K, Heinz LX, Superti-Furga G, Nagar B. Nat Commun 7, 12196, (2016). PMID: 27435900
6.Regulated secretion of acid sphingomyelinase: implications for selectivity of ceramide formation. Jenkins RW, Canals D, Idkowiak-Baldys J, Simbari F, Roddy P, Perry DM, Kitatani K, Luberto C, Hannun YA. J Biol Chem 285, 35706-18, (2010). PMID: 20807762
7.Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells. Carpinteiro A, Edwards MJ, Hoffmann M, Kochs G, Gripp B, Weigang S, Adams C, Carpinteiro E, Gulbins A, Keitsch S, Sehl C, Soddemann M, Wilker B, Kamler M, Bertsch T, Lang KS, Patel S, Wilson GC, Walter S, Hengel H, Pohlmann S, Lang PA, Kornhuber J, Becker KA, Ahmad SA, Fassbender K, Gulbins E. Cell Rep Med 1, 100142, (2020). PMID: 33163980
Cross References
Contributing Member Database Entry
- Pfam:PF19272