IPR046335
Transcriptional regulator LacI/GalR-like, sensor domain
InterPro entry
Short name | LacI/GalR-like_sensor |
Overlapping homologous superfamilies |
Description
This domain is found in a variety of transcriptional regulatory proteins from the LacI/GalR family, including HTH-type transcriptional regulators GalR, CytR, LacR and the transcriptional repressor PurR
[1]. It is related to bacterial periplasmic binding proteins, although this domain is unlikely to be found in the periplasm. This domain acts as the sensor domain which binds ligands that the DNA-binding domain responds to. This domain recognises sugars, sugar phosphates, sugar acids and purines
[2].
References
Contributing Member Database Entry
- Pfam:PF13377