IPR046947
Transcriptional regulatory protein LytR-like
InterPro entry
Short name | LytR-like |
family relationships |
Description
This family includes a group of LytTR domain-containing proteins, such as the transcriptional regulatory protein LytR and BtsR, the sensory transduction protein LytT and the Accessory gene regulator protein A. LytTR domain is a DNA-binding, potential winged helix-turn-helix (wHTH) domain
[1, 2], named after Bacillus subtilis LytT and Staphylococcus aureus lytR response regulators, involved in the regulation of cell autolysis
[1].
References
1.A novel type of conserved DNA-binding domain in the transcriptional regulators of the AlgR/AgrA/LytR family. Nikolskaya AN, Galperin MY. Nucleic Acids Res. 30, 2453-9, (2002). View articlePMID: 12034833
2.The FxRxHrS motif: a conserved region essential for DNA binding of the VirR response regulator from Clostridium perfringens. McGowan S, Lucet IS, Cheung JK, Awad MM, Whisstock JC, Rood JI. J. Mol. Biol. 322, 997-1011, (2002). View articlePMID: 12367524
GO terms
biological process
- None
cellular component
- None
Contributing Member Database Entry
- PANTHER:PTHR37299
Representative structure
4xqj: Crystal structure of AgrA LytTR domain in complex with promoters