F
IPR047696

Cell division inhibitor SulA, enterobacterial type

InterPro entry
Short nameSulA_enterobact
Overlapping
homologous
superfamilies
 
family relationships

Description

This entry represents a group of proteins specific to enterobacterales, including Cell division inhibitor SulA from Escherichia coli, a cell division inhibitor induced by the SOS response. This protein interacts with FtsZ to halt cell division
[1, 2]
. SulA proteins, like FtsZ, differ greatly by lineage, with SulA from Pseudomonas showing a different architecture.

References

1.Crystal structure of the SOS cell division inhibitor SulA and in complex with FtsZ. Cordell SC, Robinson EJ, Lowe J. Proc. Natl. Acad. Sci. U.S.A. 100, 7889-94, (2003). View articlePMID: 12808143

2.SulA inhibits assembly of FtsZ by a simple sequestration mechanism. Chen Y, Milam SL, Erickson HP. Biochemistry 51, 3100-9, (2012). PMID: 22432817

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