Iron-regulated surface determinant protein H/B, linker domain
Short name | Isd_H_B_linker |
Description
References
1.Staphylococcus aureus uses a novel multidomain receptor to break apart human hemoglobin and steal its heme. Spirig T, Malmirchegini GR, Zhang J, Robson SA, Sjodt M, Liu M, Krishna Kumar K, Dickson CF, Gell DA, Lei B, Loo JA, Clubb RT. J Biol Chem 288, 1065-78, (2013). View articlePMID: 23132864
2.Structure of the hemoglobin-IsdH complex reveals the molecular basis of iron capture by Staphylococcus aureus. Dickson CF, Kumar KK, Jacques DA, Malmirchegini GR, Spirig T, Mackay JP, Clubb RT, Guss JM, Gell DA. J Biol Chem 289, 6728-6738, (2014). View articlePMID: 24425866
3.The structure of haemoglobin bound to the haemoglobin receptor IsdH from Staphylococcus aureus shows disruption of the native α-globin haem pocket. Dickson CF, Jacques DA, Clubb RT, Guss JM, Gell DA. Acta Crystallogr D Biol Crystallogr 71, 1295-306, (2015). View articlePMID: 26057669
4.Structure-function analyses reveal key features in <i>Staphylococcus aureus</i> IsdB-associated unfolding of the heme-binding pocket of human hemoglobin. Bowden CFM, Chan ACK, Li EJW, Arrieta AL, Eltis LD, Murphy MEP. J Biol Chem 293, 177-190, (2018). View articlePMID: 29109153
Contributing Member Database Entry
- Pfam:PF20861