F
IPR049902

Fusexin 1

InterPro entry
Short nameFsx1

Description

This entry represents a small group of archaeal proteins, including Fusexin 1 from Haloferax sp. (Fsx1), which exhibits fusogenic activity and mediates cell-cell fusion in mammalian cells (bilateral fusion)
[1]
.

References

1.Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins. Moi D, Nishio S, Li X, Valansi C, Langleib M, Brukman NG, Flyak K, Dessimoz C, de Sanctis D, Tunyasuvunakool K, Jumper J, Grana M, Romero H, Aguilar PS, Jovine L, Podbilewicz B. Nat Commun 13, 3880, (2022). View articlePMID: 35794124

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