F
IPR050083

Membrane-localized HtpX protease
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameHtpX_protease
AI

Description

AI-generatedUnreviewed
The HtpX protease family is comprised of membrane-localized metalloproteases that play a role in the quality control of integral membrane proteins. Members of this family are capable of endoproteolytically degrading misfolded or overproduced membrane proteins, such as SecY, at specific cytoplasmic sites. These proteases do not require ATP for their activity, and their natural substrates are yet to be fully identified. The HtpX family is involved in the cellular process of protein turnover, particularly for the removal of damaged or non-functional membrane proteins, thereby maintaining cellular homeostasis.

Cross References

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