F
IPR050246

Class II Fructose-bisphosphate Aldolase
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameClass_II_FBP_aldolase
AI
Overlapping
homologous
superfamilies
 

Description

AI-generatedUnreviewed
The class II fructose-bisphosphate aldolase family is involved in key metabolic processes, such as glycolysis and gluconeogenesis, by catalyzing the reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to form fructose 1,6-bisphosphate. Some members also participate in the catabolism of galactitol and the metabolism of tagatose 1,6-bisphosphate, as part of the tagatose-1,6-bisphosphate aldolase complex, which requires a GatZ subunit for full activity and stability. Additionally, a subfamily within this group is responsible for producing dihydroxyacetone phosphate and malonic semialdehyde from 6-phospho-5-dehydro-2-deoxy-D-gluconate. The family includes various subunits like GatY and KbaY, indicating a diversity of functions and substrate specificities within the broader context of carbohydrate metabolism.

Cross References

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