F
IPR050524

Amino Acid-Polyamine-Organocation Superfamily YAT
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameAPC_YAT
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Description

AI-generatedUnreviewed
The amino acid-polyamine-organocation (APC) superfamily, specifically the YAT family, consists of membrane-bound permeases with broad substrate specificity. These permeases are involved in the transport of a wide range of amino acids, including but not limited to asparagine, glutamine, alanine, cysteine, glycine, isoleucine, leucine, methionine, phenylalanine, serine, threonine, tyrosine, valine, arginine, lysine, and histidine. Some members also transport related compounds such as S-adenosylmethionine, proline, and polyamines. The family plays a crucial role in the utilization of amino acids as nitrogen sources, sensing extracellular amino acid levels, and regulating the expression of amino acid-metabolizing enzymes and permeases. The permeases can function as high-affinity transporters for specific amino acids or as general permeases with broader specificity, contributing to cellular nutrition and signaling.
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