F
IPR050653

Protease Inhibitors and Growth Factor Antagonists
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameProt_Inhib_GrowthFact_Antg
AI

Description

AI-generatedUnreviewed
The protein family encompasses a group of secreted proteins that play diverse roles in physiological processes such as inhibition of proteases, antagonism of growth factors, and regulation of cell proliferation, differentiation, and immune responses. Members of the family are known to interact with and inhibit various proteases like subtilisin-like serine proteases and trypsin, as well as growth factors such as activin and TGF-beta family members. They are involved in defense mechanisms between plants and pathogens, neural induction, angiogenesis, and hematopoiesis. Some members also possess neurotoxic properties by inhibiting ion channels. The family includes proteins with kazal serine protease inhibitor signatures and those that bind directly to activin, functioning as activin antagonists, thereby regulating the biosynthesis and secretion of hormones like FSH.
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.