F
IPR050749

Glycosyl Hydrolase Family 47
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameGlycosyl_Hydrolase_47
AI
Overlapping
homologous
superfamilies
 

Description

AI-generatedUnreviewed
The glycosyl hydrolase 47 family is involved in the maturation of Asn-linked oligosaccharides, a critical process in protein quality control and degradation pathways. Members of this family function as alpha-mannosidases, which progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). This enzymatic activity is essential for the proper folding and function of glycoproteins. Some family members are also involved in early N-glycan processing, root development, and cell wall biosynthesis. The activity of these enzymes is regulated by inhibitors such as kifunensine and 1-deoxymannojirimycin, highlighting their specificity and importance in cellular metabolism.

Cross References

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