F
IPR050838

Ketopantoate reductase
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameKetopantoate_reductase
AI

Description

AI-generatedUnreviewed
The ketopantoate reductase family includes enzymes that play a crucial role in the biosynthesis of key biological molecules. Members of this family are primarily involved in the reduction of keto acids to their corresponding hydroxy acids using NAD(P)H as a cofactor. Specifically, they catalyze the conversion of ketopantoate to pantoic acid, an essential step in the biosynthesis of pantothenate (vitamin B5), which is a precursor for the synthesis of coenzyme A. Additionally, some members are involved in the biosynthesis of non-ribosomal cyclic hexadepsipeptides, such as beauvericin, by reducing ketoisovaleric acid to hydroxyisovalerate. These peptides have various biological activities, including antibiotic, antifungal, and insecticidal properties. The activity of these enzymes can be regulated by environmental stimuli and metal ions, indicating a complex interaction with cellular processes.

Cross References

Contributing Member Database Entry
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.