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IPR050862

Ribonucleoside diphosphate reductase class-2
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameRdRp_reductase_class-2
AI

Description

AI-generatedUnreviewed
The ribonucleoside diphosphate reductase class-2 family is involved in the biosynthesis of deoxyribonucleotides from ribonucleotides, providing the necessary precursors for DNA synthesis. Members of this family are vitamin B12-dependent enzymes that play a crucial role in DNA repair and replication, especially during conditions of oxygen limitation. Some family members are adenosylcobalamin-dependent ribonucleoside-triphosphate reductases, which are allosterically regulated by ATP and dNTP, indicating a sophisticated control mechanism for maintaining deoxyribonucleotide levels in the cell.

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