F
IPR050986

SIS family GutQ/KpsF subfamily isomerases
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameGutQ/KpsF_isomerases
AI
Overlapping
homologous
superfamilies
 

Description

AI-generatedUnreviewed
The GutQ/KpsF subfamily of the SIS family comprises enzymes that catalyze the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). Members of this family are involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), an essential 8-carbon sugar component of lipopolysaccharides (LPSs) in bacterial outer membranes. Some family members also participate in the biosynthesis of K-antigen capsules. The activity of these enzymes can be regulated by metal ions, and they may play a role in the regulation of the gut operon through the synthesis of the regulatory molecule A5P.

Cross References

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