IPR051018
Bacteriophage Glycosyl Hydrolase 24 AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | Bacteriophage_GH24 AI |
Overlapping homologous superfamilies |
Description
AI-generatedUnreviewed
The glycosyl hydrolase 24 family proteins are endolysins with lysozyme activity that degrade bacterial cell walls by hydrolyzing peptidoglycans. They play a crucial role in bacteriophage-mediated lysis of host cells. These proteins, along with holin, spanin, and sometimes pinholin proteins, participate in a sequential process leading to programmed host cell lysis, which facilitates the release of mature viral particles. Some members of this family are SAR-endolysins, which are tethered to the membrane by a signal-anchor sequence and released into the periplasm by the action of holin or pinholin, where they execute their lytic function.
Cross References
ENZYME
Contributing Member Database Entry
- PANTHER:PTHR38107
Representative structure
3hde: Crystal structure of full-length endolysin R21 from phage 21