IPR051078
SAGA-associated factor 11 AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | SGF11 AI |
Description
AI-generatedUnreviewed
The SGF11 family proteins are components of the SAGA complex, a transcription regulatory histone acetylation (HAT) complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Members of the SGF11 family participate in a subcomplex of SAGA that specifically deubiquitinates histone H2B, and are recruited to gene promoters by activators for transcription initiation. They are involved in nuclear receptor-mediated transactivation, mRNA binding and export from the nucleus, counteracting heterochromatin silencing, and are essential for the development of neuronal connectivity and the expression of ecdysone-induced genes.
Contributing Member Database Entry
- PANTHER:PTHR46367