F
IPR051078

SAGA-associated factor 11
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameSGF11
AI

Description

AI-generatedUnreviewed
The SGF11 family proteins are components of the SAGA complex, a transcription regulatory histone acetylation (HAT) complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Members of the SGF11 family participate in a subcomplex of SAGA that specifically deubiquitinates histone H2B, and are recruited to gene promoters by activators for transcription initiation. They are involved in nuclear receptor-mediated transactivation, mRNA binding and export from the nucleus, counteracting heterochromatin silencing, and are essential for the development of neuronal connectivity and the expression of ecdysone-induced genes.
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