IPR051122
Short-chain dehydrogenase/reductase superfamily enzyme AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | SDR_superfamily_enzyme AI |
Overlapping homologous superfamilies |
Description
AI-generatedUnreviewed
This family of proteins includes enzymes that are part of the short-chain dehydrogenases/reductases (SDR) superfamily. Members of this family are involved in various metabolic processes, including the biosynthesis of secondary metabolites, fatty acids, and siderophores, as well as the detoxification of harmful compounds. They typically exhibit NAD(H) or NADP(H) dependent oxidoreductase activity, catalyzing reactions such as the reduction of ketones to alcohols or the oxidation of alcohols to ketones. These enzymes play roles in the synthesis of complex natural products with potential pharmacological activities, regulation of iron transport and homeostasis, and conversion of cyclic substrates, which may include detoxification mechanisms.
Cross References
Contributing Member Database Entry
- PANTHER:PTHR43477