IPR051275
Cellular adhesion and signaling domain-containing protein AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | Cell_adhesion_signaling AI |
Description
AI-generatedUnreviewed
This family of proteins is involved in various cellular adhesion processes, including synaptic adhesion and the formation of specialized cell-cell junctions. Members of this family play crucial roles in the development and function of the kidney glomerular filtration barrier, as well as in the maintenance of podocyte architecture. They are also implicated in the regulation of vascular permeability and the anchoring of the podocyte slit diaphragm to the cytoskeleton. Some family members are necessary for synapse formation in the nervous system, acting as homophilic adhesion molecules that promote trans-cellular interactions and stabilize synaptic structures. Additionally, certain proteins within this family may have a role in supporting hematopoietic stem cells and regulating insulin secretion.
Contributing Member Database Entry
- PANTHER:PTHR11640
Representative structure
4of8: Crystal Structure of Rst D1-D2