IPR051335
Alanyl-tRNA Editing Enzymes AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | Alanyl-tRNA_Editing_Enzymes AI |
Overlapping homologous superfamilies |
Description
AI-generatedUnreviewed
This family of proteins functions in the editing of tRNA molecules to ensure the correct amino acid is attached. Members of this family act in trans to remove incorrect amino acid moieties from tRNA(Ala), which is charged with alanine. They are responsible for the hydrolytic editing of mischarged Ser-tRNA(Ala) and, in some cases, Gly-tRNA(Ala), preventing errors in protein synthesis. The specificity of this editing function is crucial for maintaining the fidelity of the genetic code during translation. These proteins belong to the class-II aminoacyl-tRNA synthetase family and are characterized by their ability to recognize and correct specific tRNA charging errors.
Contributing Member Database Entry
- PANTHER:PTHR43462
Representative structure
3kew: Crystal structure of probable alanyl-trna-synthase from Clostridium perfringens