F
IPR051954

tRNA (32-2'-O)-methyltransferase regulator THADA
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nametRNA_methyltransferase_THADA
AI

Description

AI-generatedUnreviewed
The THADA family proteins are involved in the post-transcriptional modification of tRNAs and energy homeostasis. Members of this family function in conjunction with specific methyltransferases to methylate the 2'-O-ribose of nucleotides at position 32 in the anticodon loop of tRNAs, a modification important for the stability and function of the tRNA molecule. Additionally, THADA proteins play a crucial role in regulating metabolic processes. They are implicated in the control of calcium signaling pathways that influence energy storage and thermogenesis. By modulating the activity of calcium-transporting ATPases, THADA proteins can affect lipid storage and heat production, and may also influence feeding behavior through actions in the nervous system.
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