F
IPR052069

Calcium-regulated mRNA-binding domain-containing protein
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameCa-reg_mRNA-binding_domain
AI
Overlapping
homologous
superfamilies
 

Description

AI-generatedUnreviewed
This family of proteins includes RNA-binding factors that are involved in the regulation of mRNA stability and the synthesis of histone variants. Members of this family have been shown to bind specifically to mRNA, including the 3'-UTR ends of histone H1 and H3.3 mRNAs, which encompasses the polyadenylation signal. This binding activity suggests a role in the post-transcriptional regulation of gene expression. Some members are also known to bind single-stranded DNA in vitro. The functions of these proteins are crucial in processes such as the negative regulation of histone variant synthesis, particularly in the context of brain development. The calcium-regulated members of this family are responsive to changes in intracellular calcium levels, which may influence their interaction with target mRNAs.
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