IPR052105
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | MGAT5_Glycosyltransferase AI |
Description
AI-generatedUnreviewed
This family of proteins includes glycosyltransferases involved in the modification of glycoproteins by catalyzing the addition of N-acetylglucosamine (GlcNAc) to mannose residues in N-linked oligosaccharides. These enzymes play a crucial role in the biosynthesis of branched, complex-type N-glycans, which are essential for proper protein folding, stability, and function. The activity of these proteins is important for cellular processes such as signaling pathway activation, actin cytoskeleton reorganization, cell-cell adhesion, cell migration, and the inflammatory response. They are also involved in modulating the interactions between growth factors and their receptors, affecting processes like angiogenesis and leukocyte evasion. Additionally, they contribute to the regulation of integrin and laminin-mediated neuronal cell adhesion and migration.
Cross References
Contributing Member Database Entry
- PANTHER:PTHR15075