F
IPR052290

Sphingolipid C9-methyltransferase
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameSphingo_C9-MT
AI
Overlapping
homologous
superfamilies
 

Description

AI-generatedUnreviewed
This family of proteins catalyzes the methylation of the sphingoid base component of glucosylceramides at the C9-position. The specific activity involves the use of 4,8-desaturated ceramides as substrates. These enzymes play a pivotal role in the growth, differentiation, and pathogenicity of fungi. The addition of a methyl group at the C9-position of glucosylceramides is a distinctive feature of fungal sphingolipids, setting them apart from those found in plants and animals. This modification is thought to be significant in host-pathogen interactions, potentially aiding in the recognition of fungal invasion by the host and the triggering of defense responses. However, the C9-methylation is not essential for certain interactions, such as the sensitivity to specific plant defensins.

Cross References

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