F
IPR052551

UV-induced DNA damage repair photolyase
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameUV-DNA_repair_photolyase
AI
Overlapping
homologous
superfamilies
 

Description

AI-generatedUnreviewed
This family of proteins includes members involved in the repair of UV-induced DNA damage, specifically (6-4) lesions. One characterized member functions as a photolyase, utilizing blue-light energy to catalyze the photoreactivation of (6-4) pyrimidine-pyrimidone photoproducts in both single-stranded and double-stranded DNA. The family is related to the iron-sulfur bacterial cryptochrome/photolyase (FeS-BCP) group, suggesting a conserved mechanism involving electron transfer facilitated by iron-sulfur clusters. The presence of uncharacterized members indicates potential functional diversity within the family.

Cross References

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