F
IPR000256

Influenza A virus NS1 protein

InterPro entry
Short nameNS1A
Overlapping
homologous
superfamilies
 
family relationships

Description

NS1 is a homodimeric RNA-binding protein found in influenza virus that is required for viral replication. NS1 binds polyA tails of mRNA keeping them in the nucleus. NS1 inhibits pre-mRNA splicing by tightly binding to a specific stem-bulge of U6 snRNA
[1]
.

References

1.A novel RNA-binding motif in influenza A virus non-structural protein 1. Chien CY, Tejero R, Huang Y, Zimmerman DE, Rios CB, Krug RM, Montelione GT. Nat. Struct. Biol. 4, 891-5, (1997). View articlePMID: 9360601

GO terms

biological process

  • None

molecular function

cellular component

  • None

Cross References

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