Ras-like guanine nucleotide exchange factor, N-terminal
Short name | Ras-like_Gua-exchang_fac_N |
Overlapping homologous superfamilies |
Description
References
1.The structural basis of the activation of Ras by Sos. Boriack-Sjodin PA, Margarit SM, Bar-Sagi D, Kuriyan J. Nature 394, 337-43, (1998). View articlePMID: 9690470
2.GEFs in growth factor signaling. Bernards A, Settleman J. Growth Factors 25, 355-61, (2007). View articlePMID: 18236214
3.Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins. Quilliam LA, Khosravi-Far R, Huff SY, Der CJ. Bioessays 17, 395-404, (1995). View articlePMID: 7786285
4.Proteins regulating Ras and its relatives. Boguski MS, McCormick F. Nature 366, 643-54, (1993). View articlePMID: 8259209
5.Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J. Nature 363, 85-8, (1993). View articlePMID: 8479541
6.Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state. Rehmann H, Das J, Knipscheer P, Wittinghofer A, Bos JL. Nature 439, 625-8, (2006). View articlePMID: 16452984
7.Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Cell 112, 685-95, (2003). View articlePMID: 12628188
8.Many faces of Ras activation. Buday L, Downward J. Biochim. Biophys. Acta 1786, 178-87, (2008). View articlePMID: 18541156