F
IPR001640

Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase Lgt

InterPro entry
Short nameLgt

Description

Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase lgt
[1]
is an integral membrane enzyme that catalyses the first reaction of the three-step post-translational lipid modification
[2]
. It transfers the n-acyl diglyceride group onto what will become the N-terminal cysteine of membrane lipoproteins. This enzyme is an integral membrane protein.

References

1.Lipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol. Sankaran K, Wu HC. J. Biol. Chem. 269, 19701-6, (1994). View articlePMID: 8051048

2.Crystal structure of E. coli lipoprotein diacylglyceryl transferase. Mao G, Zhao Y, Kang X, Li Z, Zhang Y, Wang X, Sun F, Sankaran K, Zhang XC. Nat Commun 7, 10198, (2016). View articlePMID: 26729647

GO terms

Cross References

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