IPR011115
SecA DEAD-like, N-terminal
InterPro entry
Short name | SecA_DEAD |
Overlapping homologous superfamilies |
Description
SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP-dependent manner
[1, 2, 3]. This domain represents the N-terminal ATP-dependent helicase domain.
References
1.Amino-terminal region of SecA is involved in the function of SecG for protein translocation into Escherichia coli membrane vesicles. Mori H, Sugiyama H, Yamanaka M, Sato K, Tagaya M, Mizushima S. J. Biochem. 124, 122-9, (1998). View articlePMID: 9644254
2.SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of Escherichia coli. Lill R, Cunningham K, Brundage LA, Ito K, Oliver D, Wickner W. EMBO J. 8, 961-6, (1989). View articlePMID: 2542029
GO terms
biological process
molecular function
cellular component