D
IPR011115

SecA DEAD-like, N-terminal

InterPro entry
Short nameSecA_DEAD
Overlapping
homologous
superfamilies
 

Description

SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP-dependent manner
[1, 2, 3]
. This domain represents the N-terminal ATP-dependent helicase domain.

References

1.Amino-terminal region of SecA is involved in the function of SecG for protein translocation into Escherichia coli membrane vesicles. Mori H, Sugiyama H, Yamanaka M, Sato K, Tagaya M, Mizushima S. J. Biochem. 124, 122-9, (1998). View articlePMID: 9644254

2.SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of Escherichia coli. Lill R, Cunningham K, Brundage LA, Ito K, Oliver D, Wickner W. EMBO J. 8, 961-6, (1989). View articlePMID: 2542029

3.Plastids contain a second sec translocase system with essential functions. Skalitzky CA, Martin JR, Harwood JH, Beirne JJ, Adamczyk BJ, Heck GR, Cline K, Fernandez DE. Plant Physiol 155, 354-69, (2011). PMID: 21051552

GO terms

biological process

molecular function

cellular component

Cross References

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