F
IPR011683

Glycosyl hydrolase family 53

InterPro entry
Short nameGlyco_hydro_53
Overlapping
homologous
superfamilies
 

Description

O-Glycosyl hydrolases (
3.2.1.
) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families
[3, 4]
. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.

Proteins in this family are endo-1,4- beta-galactanases (
3.2.1.89
)
[1]
. They have a TIM barrel fold
[2]
.

References

1.Role of the ganSPQAB Operon in Degradation of Galactan by Bacillus subtilis. Watzlawick H, Morabbi Heravi K, Altenbuchner J. J Bacteriol 198, 2887-96, (2016). PMID: 27501980

2.Aspergillus aculeatus beta-1,4-galactanase: substrate recognition and relations to other glycoside hydrolases in clan GH-A. Ryttersgaard C, Lo Leggio L, Coutinho PM, Henrissat B, Larsen S. Biochemistry 41, 15135-43, (2002). View articlePMID: 12484750

3.Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G. Proc. Natl. Acad. Sci. U.S.A. 92, 7090-4, (1995). View articlePMID: 7624375

4.Structures and mechanisms of glycosyl hydrolases. Davies G, Henrissat B. Structure 3, 853-9, (1995). View articlePMID: 8535779

GO terms

biological process

  • None

cellular component

  • None

Cross References

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