D
IPR013894

RecQ mediated genome instability protein 1, OB-fold domain

InterPro entry
Short nameRMI1_OB
Overlapping
homologous
superfamilies
 

Description

This entry represents the the OB-fold domain of RMI1 (RecQ-mediated genome instability protein 1) and similar proteins
[1]
. This domain forms a stable complex with Bloom syndrome protein BLM and DNA topoisomerase 3-alpha
[2]
.

References

1.RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Xu D, Guo R, Sobeck A, Bachrati CZ, Yang J, Enomoto T, Brown GW, Hoatlin ME, Hickson ID, Wang W. Genes Dev. 22, 2843-55, (2008). View articlePMID: 18923082

2.BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome. Singh TR, Ali AM, Busygina V, Raynard S, Fan Q, Du CH, Andreassen PR, Sung P, Meetei AR. Genes Dev. 22, 2856-68, (2008). View articlePMID: 18923083

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