F
IPR014190

Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase

InterPro entry
Short namePTGR1
Overlapping
homologous
superfamilies
 
family relationships

Description

Leukotriene B4 12-hydroxydehydrogenase is an NADP-dependent enzyme of arachidonic acid metabolism, responsible for converting leukotriene B4 to the much less active metabolite 12-oxo-leukotriene B4. The BRENDA database lists leukotriene B4 12-hydroxydehydrogenase as one of the synonyms of 2-alkenal reductase (
1.3.1.74
), while
1.3.1.48
is 15-oxoprostaglandin 13-reductase.

GO terms

Cross References

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