H
IPR014710

RmlC-like jelly roll fold

InterPro entry
Short nameRmlC-like_jellyroll
Overlapping entries
 
Cupin 1 (IPR006045)

Description

RmlC (deoxythymidine diphosphates-4-dehydrorhamnose 3,5-epimerase;
5.1.3.13
) is a mainly beta class protein with a jelly roll-like topology. It is a dTDP-sugar isomerase enzyme involved in the synthesis of L-rhamnose, a saccharide required for the virulence of some pathogenic bacteria
[1]
. This entry represents the domain with the jelly roll-like fold.

References

1.RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase. Giraud MF, Leonard GA, Field RA, Berlind C, Naismith JH. Nat. Struct. Biol. 7, 398-402, (2000). View articlePMID: 10802738

Further reading

2. Germin is a manganese containing homohexamer with oxalate oxidase and superoxide dismutase activities. Woo EJ, Dunwell JM, Goodenough PW, Marvier AC, Pickersgill RW. Nat. Struct. Biol. 7, 1036-40, (2000). View articlePMID: 11062559

3. Crystal structure of auxin-binding protein 1 in complex with auxin. Woo EJ, Marshall J, Bauly J, Chen JG, Venis M, Napier RM, Pickersgill RW. EMBO J. 21, 2877-85, (2002). View articlePMID: 12065401

4. Crystal structure of soybean proglycinin A1aB1b homotrimer. Adachi M, Takenaka Y, Gidamis AB, Mikami B, Utsumi S. J. Mol. Biol. 305, 291-305, (2001). View articlePMID: 11124907

5. Modeling and experiment yields the structure of acireductone dioxygenase from Klebsiella pneumoniae. Pochapsky TC, Pochapsky SS, Ju T, Mo H, Al-Mjeni F, Maroney MJ. Nat. Struct. Biol. 9, 966-72, (2002). View articlePMID: 12402029

6. Crystal structure of the copper-containing quercetin 2,3-dioxygenase from Aspergillus japonicus. Fusetti F, Schroter KH, Steiner RA, van Noort PI, Pijning T, Rozeboom HJ, Kalk KH, Egmond MR, Dijkstra BW. Structure 10, 259-68, (2002). View articlePMID: 11839311

7. The x-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution. Cleasby A, Wonacott A, Skarzynski T, Hubbard RE, Davies GJ, Proudfoot AE, Bernard AR, Payton MA, Wells TN. Nat. Struct. Biol. 3, 470-9, (1996). View articlePMID: 8612079

8. Crystal structure of human homogentisate dioxygenase. Titus GP, Mueller HA, Burgner J, Rodriguez De Cordoba S, Penalva MA, Timm DE. Nat. Struct. Biol. 7, 542-6, (2000). View articlePMID: 10876237

9. Transcription activation by CooA, the CO-sensing factor from Rhodospirillum rubrum. The interaction between CooA and the C-terminal domain of the alpha subunit of RNA polymerase. He Y, Gaal T, Karls R, Donohue TJ, Gourse RL, Roberts GP. J. Biol. Chem. 274, 10840-5, (1999). View articlePMID: 10196160

10. cAMP Modulation of the cytoplasmic domain in the HCN2 channel investigated by molecular simulations. Berrera M, Pantano S, Carloni P. Biophys. J. 90, 3428-33, (2006). View articlePMID: 16500960

11. Structure of the CO sensing transcription activator CooA. Lanzilotta WN, Schuller DJ, Thorsteinsson MV, Kerby RL, Roberts GP, Poulos TL. Nat. Struct. Biol. 7, 876-80, (2000). View articlePMID: 11017196

Cross References

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