D
IPR015345

Cytokinin dehydrogenase 1, FAD/cytokinin binding domain

InterPro entry
Short nameCytokinin_DH_FAD/cytokin-bd
Overlapping
homologous
superfamilies
 

Description

This domain adopts an α+β sandwich structure with an antiparallel β-sheet, in a ferredoxin-like fold. It is predominantly found in plant cytokinin dehydrogenase 1, where it is capable of binding both FAD and cytokinin substrates. The substrate displays a 'plug-into-socket' binding mode that seals the catalytic site and precisely positions the carbon atom undergoing oxidation in close contact with the reactive locus of the flavin
[1]
.

References

1.Structures of Michaelis and product complexes of plant cytokinin dehydrogenase: implications for flavoenzyme catalysis. Malito E, Coda A, Bilyeu KD, Fraaije MW, Mattevi A. J. Mol. Biol. 341, 1237-49, (2004). View articlePMID: 15321719

GO terms

Cross References

Contributing Member Database Entry
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