D
IPR016140

Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain

InterPro entry
Short nameBifunc_inhib/LTP/seed_store
Overlapping
homologous
superfamilies
 
domain relationships

Description

This entry represents a structural domain consisting of 4-helices with a folded leaf topology, and forming a right-handed superhelix. This domain occurs in several proteins, including:


 * Plant lipid-transfer proteins, such as the non-specific lipid-transfer proteins ns-LTP1 and ns-LTP2
[1, 2]
.
 * Proteinase/alpha-amylase inhibitors, such as trypsin/alpha-amylase inhibitor RBI from Eleusine coracana (Indian finger millet)
[3]
and Hageman factor/amylase inhibitor from Zea mays (Maize)
[4]
.
 * Seed storage proteins, such as napin from Brassica napus (Rape)
[5]
and 2S albumin from Ricinus communis (Castor bean)
[6]
.

References

1.The crystal structure of a wheat nonspecific lipid transfer protein (ns-LTP1) complexed with two molecules of phospholipid at 2.1 A resolution. Charvolin D, Douliez JP, Marion D, Cohen-Addad C, Pebay-Peyroula E. Eur. J. Biochem. 264, 562-8, (1999). View articlePMID: 10491104

2.Solution structure of plant nonspecific lipid transfer protein-2 from rice (Oryza sativa). Samuel D, Liu YJ, Cheng CS, Lyu PC. J. Biol. Chem. 277, 35267-73, (2002). View articlePMID: 12011089

3.A novel strategy for inhibition of alpha-amylases: yellow meal worm alpha-amylase in complex with the Ragi bifunctional inhibitor at 2.5 A resolution. Strobl S, Maskos K, Wiegand G, Huber R, Gomis-Ruth FX, Glockshuber R. Structure 6, 911-21, (1998). View articlePMID: 9687373

4.Structural determinants of the bifunctional corn Hageman factor inhibitor: x-ray crystal structure at 1.95 A resolution. Behnke CA, Yee VC, Trong IL, Pedersen LC, Stenkamp RE, Kim SS, Reeck GR, Teller DC. Biochemistry 37, 15277-88, (1998). View articlePMID: 9799488

5.1H NMR assignment and global fold of napin BnIb, a representative 2S albumin seed protein. Rico M, Bruix M, Gonzalez C, Monsalve RI, Rodriguez R. Biochemistry 35, 15672-82, (1996). View articlePMID: 8961930

6.Solution structure of RicC3, a 2S albumin storage protein from Ricinus communis. Pantoja-Uceda D, Bruix M, Gimenez-Gallego G, Rico M, Santoro J. Biochemistry 42, 13839-47, (2003). View articlePMID: 14636051

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.