F
IPR017665

Guanylate kinase

InterPro entry
Short nameGuanylate_kinase
Overlapping
homologous
superfamilies
 

Description

Guanylate kinase, also called GMP kinase, is essential for recycling GMP and indirectly, cGMP. This enzyme transfers a phosphate from ATP to GMP, yielding ADP and GDP
[1]
. Guanylate kinase is a highly conserved monomer and is important for the activation of various antiviral drugs.

References

1.Structural characterization of the closed conformation of mouse guanylate kinase. Sekulic N, Shuvalova L, Spangenberg O, Konrad M, Lavie A. J. Biol. Chem. 277, 30236-43, (2002). View articlePMID: 12036965

GO terms

cellular component

  • None

Cross References

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