Protein kinase, C-terminal
Short name | Pkinase_C |
Overlapping homologous superfamilies | |
domain relationships |
Description
* Serine/threonine-protein kinases
* Tyrosine-protein kinases
* Dual specificity protein kinases (e.g. MEK -phosphorylates both Thr and Tyr on target proteins)
References
1.The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Hanks SK, Quinn AM, Hunter T. Science 241, 42-52, (1988). View articlePMID: 3291115
2.Evolution of protein kinase signaling from yeast to man. Manning G, Plowman GD, Hunter T, Sudarsanam S. Trends Biochem. Sci. 27, 514-20, (2002). View articlePMID: 12368087
3.High-throughput structural biology in drug discovery: protein kinases. Stout TJ, Foster PG, Matthews DJ. Curr. Pharm. Des. 10, 1069-82, (2004). View articlePMID: 15078142
4.Creating chemical diversity to target protein kinases. Li B, Liu Y, Uno T, Gray N. Comb. Chem. High Throughput Screen. 7, 453-72, (2004). View articlePMID: 15320712
5.The protein kinase complement of the human genome. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. Science 298, 1912-34, (2002). View articlePMID: 12471243
GO terms
biological process
cellular component
- None
Cross References
Contributing Member Database Entry
- Pfam:PF00433