IPR022781
Flagellar biosynthesis protein, FliO
InterPro entry
Short name | Flagellar_biosynth_FliO |
Description
FliO is an essential component of the flagellum-specific protein export apparatus
[1]. It is an integral membrane protein that acts as an assembly chaperone for the flagellar protein FliP. It is crucial, although not strictly required, for efficient FliP assembly and, thus flagellar assembly and function
[2]. FliO is a short protein found in flagellar biosynthesis operons, and which contains a highly hydrophobic N-terminal sequence followed generally by two basic amino acids. This region is reminiscent of but distinct from the twin-arginine translocation signal sequence. Some instances of this gene have been named "FliZ" but phylogenetic tree building supports a single FliO family.
References
1.Components of the Salmonella flagellar export apparatus and classification of export substrates. Minamino T, Macnab RM. J. Bacteriol. 181, 1388-94, (1999). View articlePMID: 10049367
2.A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum. Fabiani FD, Renault TT, Peters B, Dietsche T, Galvez EJC, Guse A, Freier K, Charpentier E, Strowig T, Franz-Wachtel M, Macek B, Wagner S, Hensel M, Erhardt M. PLoS Biol 15, e2002267, (2017). PMID: 28771474
GO terms
biological process
molecular function
- None
cellular component
Cross References
Genome Properties