F
IPR022781

Flagellar biosynthesis protein, FliO

InterPro entry
Short nameFlagellar_biosynth_FliO

Description

FliO is an essential component of the flagellum-specific protein export apparatus
[1]
. It is an integral membrane protein that acts as an assembly chaperone for the flagellar protein FliP. It is crucial, although not strictly required, for efficient FliP assembly and, thus flagellar assembly and function
[2]
. FliO is a short protein found in flagellar biosynthesis operons, and which contains a highly hydrophobic N-terminal sequence followed generally by two basic amino acids. This region is reminiscent of but distinct from the twin-arginine translocation signal sequence. Some instances of this gene have been named "FliZ" but phylogenetic tree building supports a single FliO family.

References

1.Components of the Salmonella flagellar export apparatus and classification of export substrates. Minamino T, Macnab RM. J. Bacteriol. 181, 1388-94, (1999). View articlePMID: 10049367

2.A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum. Fabiani FD, Renault TT, Peters B, Dietsche T, Galvez EJC, Guse A, Freier K, Charpentier E, Strowig T, Franz-Wachtel M, Macek B, Wagner S, Hensel M, Erhardt M. PLoS Biol 15, e2002267, (2017). PMID: 28771474

GO terms

molecular function

  • None

cellular component

Cross References

Contributing Member Database Entries
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.