H
IPR023476

Peptidyl-tRNA hydrolase II domain superfamily

InterPro entry
Short namePep_tRNA_hydro_II_dom_sf
Overlapping entries
 

Description

Peptidyl-tRNA hydrolases are enzymes that release tRNAs from peptidyl-tRNA during translation
[1]
.

This superfamily represents the structural domain found in these t-RNA hydrolases and which form dimers
[2]
.

References

1.Orthologs of a novel archaeal and of the bacterial peptidyl-tRNA hydrolase are nonessential in yeast. Rosas-Sandoval G, Ambrogelly A, Rinehart J, Wei D, Cruz-Vera LR, Graham DE, Stetter KO, Guarneros G, Soll D. Proc. Natl. Acad. Sci. U.S.A. 99, 16707-12, (2002). View articlePMID: 12475929

2.Crystal structure at 1.8 A resolution and identification of active site residues of Sulfolobus solfataricus peptidyl-tRNA hydrolase. Fromant M, Schmitt E, Mechulam Y, Lazennec C, Plateau P, Blanquet S. Biochemistry 44, 4294-301, (2005). View articlePMID: 15766258

Cross References

Contributing Member Database Entries
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.