D
IPR025709

Leucyl-tRNA synthetase, editing domain

InterPro entry
Short nameLeu_tRNA-synth_edit
Overlapping
homologous
superfamilies
 

Description

This entry represents the editing domain (known as CP1 domain) of Leucyl-tRNA synthetase (
6.1.1.4
), which hydrolyses mischarged tRNALeu. In the case of Leucyl-tRNA synthetase, the β-strands that link the CP1 domain to the aminoacylation core of the protein are also required for editing activity
[1]
.

References

1.Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activity. Betha AK, Williams AM, Martinis SA. Biochemistry 46, 6258-67, (2007). View articlePMID: 17474713

GO terms

Cross References

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.