IPR025932
Trypanosome variant surface glycoprotein, B-type, N-terminal domain
InterPro entry
Short name | Trypano_VSG_B_N_dom |
Description
This entry represents the N-terminal of B-type variant surface glycoproteins (VSG) from trypanosomal parasites.
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes
[1].
References
1.Sequences of three VSG mRNAs expressed in a mixed population of Trypanosoma brucei rhodesiense. Reddy LV, Hall T, Donelson JE. Biochem. Biophys. Res. Commun. 169, 730-6, (1990). View articlePMID: 2357229
Contributing Member Database Entry
- Pfam:PF13206
Representative structure
8b3w: Structure of metacyclic VSG (mVSG) 1954 from Trypanosoma brucei