IPR027363
Methylthioribose-1-phosphate isomerase, N-terminal
InterPro entry
Short name | M1Pi_N |
Overlapping entries |
Description
Methylthioribose-1-phosphate isomerase, an enzyme of the methionine salvage pathway, catalyses the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
[1].
The enzyme can be divided into two domains, the N-terminal domain and the C-terminal domain. The N-terminal domain folds into a three-stranded antiparallel β-sheet followed by five α-helices
[2].
References
1.A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO. Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A. Science 302, 286-90, (2003). View articlePMID: 14551435
2.Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: implications for catalytic mechanism. Tamura H, Saito Y, Ashida H, Inoue T, Kai Y, Yokota A, Matsumura H. Protein Sci. 17, 126-35, (2008). View articlePMID: 18156470
Cross References
Contributing Member Database Entry
- CATH-Gene3D:G3DSA:1.20.120.420