H
IPR027363

Methylthioribose-1-phosphate isomerase, N-terminal

InterPro entry
Short nameM1Pi_N
Overlapping entries
 

Description

Methylthioribose-1-phosphate isomerase, an enzyme of the methionine salvage pathway, catalyses the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
[1]
.

The enzyme can be divided into two domains, the N-terminal domain and the C-terminal domain. The N-terminal domain folds into a three-stranded antiparallel β-sheet followed by five α-helices
[2]
.

References

1.A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO. Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A. Science 302, 286-90, (2003). View articlePMID: 14551435

2.Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: implications for catalytic mechanism. Tamura H, Saito Y, Ashida H, Inoue T, Kai Y, Yokota A, Matsumura H. Protein Sci. 17, 126-35, (2008). View articlePMID: 18156470

Cross References

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