H
IPR029017

Enolase-like, N-terminal

InterPro entry
Short nameEnolase-like_N
Overlapping entries
 

Description

This superfamily represents the N-terminal of the enolase and similar structural domains found in several enzymes, such as D-glucarate dehydratases, muconate-lactonizing enzymes, mandelate racemases, d-galactonate dehydratase, O-succinylbenzoate synthases and chlormuconate cycloisomerases, l-Ala-d/l-Glu epimerases, 3-methylaspartate ammonia lyase, etc
[1]
. These enzymes share a bidomain structure containing a capping domain and a C-terminal barrel domain. The N-terminal domain forms part of the capping domain
[1]
.

References

1.Divergent evolution in the enolase superfamily: the interplay of mechanism and specificity. Gerlt JA, Babbitt PC, Rayment I. Arch. Biochem. Biophys. 433, 59-70, (2005). View articlePMID: 15581566

Cross References

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