IPR032818
DedA-like
InterPro entry
Short name | DedA-like |
Description
This entry represents the DedA family of proteins which includes the inner membrane proteins YghB, YqjA, and DedA. DedA may be involved in undecaprenyl phosphate (UndP) transport and recycling
[1]. YghB may be a membrane transporter required for proton motive force (PMF)-dependent drug efflux. It required, with YqjA, for the proper export of certain periplasmic amidases and, possibly, other Tat substrates. It may play a role in determining membrane lipid composition
[2].
References
1.Two broadly conserved families of polyprenyl-phosphate transporters. Roney IJ, Rudner DZ. Nature 613, 729-734, (2023). View articlePMID: 36450357
2.Members of the conserved DedA family are likely membrane transporters and are required for drug resistance in Escherichia coli. Kumar S, Doerrler WT. Antimicrob Agents Chemother 58, 923-30, (2014). View articlePMID: 24277026
Contributing Member Database Entry
- PANTHER:PTHR30353