F
IPR032818

DedA-like

InterPro entry
Short nameDedA-like

Description

This entry represents the DedA family of proteins which includes the inner membrane proteins YghB, YqjA, and DedA. DedA may be involved in undecaprenyl phosphate (UndP) transport and recycling
[1]
. YghB may be a membrane transporter required for proton motive force (PMF)-dependent drug efflux. It required, with YqjA, for the proper export of certain periplasmic amidases and, possibly, other Tat substrates. It may play a role in determining membrane lipid composition
[2]
.

References

1.Two broadly conserved families of polyprenyl-phosphate transporters. Roney IJ, Rudner DZ. Nature 613, 729-734, (2023). View articlePMID: 36450357

2.Members of the conserved DedA family are likely membrane transporters and are required for drug resistance in Escherichia coli. Kumar S, Doerrler WT. Antimicrob Agents Chemother 58, 923-30, (2014). View articlePMID: 24277026

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