D
IPR033937

Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain

InterPro entry
Short nameMGS_CPS_CarB
Overlapping
homologous
superfamilies
 
domain relationships

Description

This entry represents the methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways responsible for the synthesis of pyrimidine nucleotides or arginine. The MGS-like domain is the C-terminal domain of CarB and appears to play a regulatory role in CPS function by binding allosteric effector molecules, including UMP and ornithine
[1]
.

References

1.Carbamoyl phosphate synthetase: an amazing biochemical odyssey from substrate to product. Holden HM, Thoden JB, Raushel FM. Cell. Mol. Life Sci. 56, 507-22, (1999). View articlePMID: 11212301

Cross References

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