Aminopeptidase, leukotriene A4 hydrolase-like
Short name | M1_LTA4H |
Overlapping homologous superfamilies | |
family relationships |
Description
References
1.Structure and catalytic mechanisms of leukotriene A4 hydrolase. Haeggstrom JZ, Tholander F, Wetterholm A. Prostaglandins Other Lipid Mediat. 83, 198-202, (2007). View articlePMID: 17481555
2.Modulating the substrate specificity of LTA4H aminopeptidase by using chemical compounds and small-molecule-guided mutagenesis. Jiang X, Zhou L, Wu Y, Wei D, Sun C, Jia J, Liu Y, Lai L. Chembiochem 11, 1120-8, (2010). View articlePMID: 20432426
3.Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase. Oi N, Jeong CH, Nadas J, Cho YY, Pugliese A, Bode AM, Dong Z. Cancer Res. 70, 9755-64, (2010). View articlePMID: 20952510
4.Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms. Rudberg PC, Tholander F, Thunnissen MM, Haeggstrom JZ. J. Biol. Chem. 277, 1398-404, (2002). View articlePMID: 11675384
5.Crystal structure of leukotriene A4 hydrolase in complex with kelatorphan, implications for design of zinc metallopeptidase inhibitors. Tholander F, Roques BP, Fournie-Zaluski MC, Thunnissen MM, Haeggstrom JZ. FEBS Lett. 584, 3446-51, (2010). View articlePMID: 20609366
6.Structures and mechanisms of enzymes in the leukotriene cascade. Rinaldo-Matthis A, Haeggstrom JZ. Biochimie 92, 676-81, (2010). View articlePMID: 20097252
7.Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness. Rao NL, Riley JP, Banie H, Xue X, Sun B, Crawford S, Lundeen KA, Yu F, Karlsson L, Fourie AM, Dunford PJ. Am. J. Respir. Crit. Care Med. 181, 899-907, (2010). View articlePMID: 20110560
Cross References
Contributing Member Database Entry
- PANTHER:PTHR45726