F
IPR034697

Baseplate wedge protein gp7

InterPro entry
Short nameGP7_T4

Description

This family includes baseplate wedge protein gp7 (gp7) from bacteriophage T4 and its relatives. Contractile tail bacteriophages use a multiprotein tubular apparatus resembling a coiled spring wound round a rigid tube to attach to and penetrate host cell membranes. The structure known as the baseplate replays the contraction signal to the sheath
[1, 2]
. gp7 is an intermediate (or inner) baseplate protein involved in tail assembly
[3]
. It also forms a complex with gp25 and two molecules of gp6 which is involved in sheath contraction
[1]
.

References

1.Structure of the T4 baseplate and its function in triggering sheath contraction. Taylor NM, Prokhorov NS, Guerrero-Ferreira RC, Shneider MM, Browning C, Goldie KN, Stahlberg H, Leiman PG. Nature 533, 346-52, (2016). View articlePMID: 27193680

2.Three-dimensional rearrangement of proteins in the tail of bacteriophage T4 on infection of its host. Leiman PG, Chipman PR, Kostyuchenko VA, Mesyanzhinov VV, Rossmann MG. Cell 118, 419-29, (2004). View articlePMID: 15315755

3.Morphogenesis of the T4 tail and tail fibers. Leiman PG, Arisaka F, van Raaij MJ, Kostyuchenko VA, Aksyuk AA, Kanamaru S, Rossmann MG. Virol. J. 7, 355, (2010). View articlePMID: 21129200

GO terms

biological process

  • None

molecular function

  • None
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