H
IPR035443

Herpesvirus protease superfamily

InterPro entry
Short nameHerpes_virus_sf
Overlapping entries
 
Peptidase S21 (IPR001847)

Description

Herpesvirus protease is required for the life cycle of the virus and is an attractive target for the design and development of new anti-herpes agents. The protease belongs to a new class of serine proteases, with a novel backbone fold and a unique Ser-His-His catalytic triad
[1]
.

References

1.Structural and biochemical studies of inhibitor binding to human cytomegalovirus protease. Khayat R, Batra R, Qian C, Halmos T, Bailey M, Tong L. Biochemistry 42, 885-91, (2003). View articlePMID: 12549906

Cross References

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