D
IPR035808

Large ribosomal subunit protein uL30, eukaryotic/archaeal

InterPro entry
Short nameRibosomal_uL30_euk_arc
Overlapping
homologous
superfamilies
 

Description

This entry represents a structural domain of the large ribosomal subunit protein uL30 from eukaryotes and archaea (which are also known as L7 subunit) and the ribosome biogenesis protein RLP7 (ribosomal protein L7-like) from yeasts. RLP7 is required for the biogenesis of the 60S ribosomal subunit
[2, 3, 4, 5]
.

Ribosomal protein uL30 is one of the proteins from the large ribosomal subunit. uL30 belongs to a family of ribosomal proteins which, on the basis of sequence similarities
[1]
, groups bacteria and archaea L30, yeast mitochondrial L33, and Drosophila melanogaster, Dictyostelium discoideum (Slime mold), fungal and mammalian uL7 ribosomal proteins. uL30 from bacteria are small proteins of about 60 residues, those from archaea are proteins of about 150 residues, and eukaryotic L7 are proteins of about 250 to 270 residues.

References

1.Yeast ribosomal proteins: XIII. Saccharomyces cerevisiae YL8A gene, interrupted with two introns, encodes a homolog of mammalian L7. Mizuta K, Hashimoto T, Otaka E. Nucleic Acids Res. 20, 1011-6, (1992). View articlePMID: 1549461

2.A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis. Dunbar DA, Dragon F, Lee SJ, Baserga SJ. Proc. Natl. Acad. Sci. U.S.A. 97, 13027-32, (2000). View articlePMID: 11087857

3.The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Ban N, Nissen P, Hansen J, Moore PB, Steitz TA. Science 289, 905-20, (2000). View articlePMID: 10937989

4.Crystal structure of the eukaryotic ribosome. Ben-Shem A, Jenner L, Yusupova G, Yusupov M. Science 330, 1203-9, (2010). View articlePMID: 21109664

5.Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles. Babiano R, Badis G, Saveanu C, Namane A, Doyen A, Diaz-Quintana A, Jacquier A, Fromont-Racine M, de la Cruz J. Nucleic Acids Res. 41, 9461-70, (2013). View articlePMID: 23945946

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.