H
IPR036968

Enolpyruvate transferase domain superfamily

InterPro entry
Short nameEnolpyruvate_Tfrase_sf
Overlapping entries
 

Description

5-enolpyruvylshikimate 3-phosphate synthase (EPSPS), also known as 3-phosphoshikimate 1-carboxyvinyltransferase, and UDP-N-acetylglucosamine enolpyruvyl transferase (MurA), also known as UDP-N-acetylglucosamine 1-carboxyvinyltransferase, have both a unique three-dimensional topology and overall reaction mechanism in common
[1]
. This entry represents the core domain superfamily of EPSPS and MurA, which transfers enolpryruvate from phosphoenolpyruvate to 3-phosphoshikimate and UDP-N-acetyl-alpha-D-glucosamine respectively.

References

1.Substrate and inhibitor-induced conformational changes in the structurally related enzymes UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS). Krekel F, Oecking C, Amrhein N, Macheroux P. Biochemistry 38, 8864-78, (1999). View articlePMID: 10413459

GO terms

biological process

  • None

cellular component

  • None

Cross References

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