IPR036968
Enolpyruvate transferase domain superfamily
InterPro entry
Short name | Enolpyruvate_Tfrase_sf |
Overlapping entries |
Description
5-enolpyruvylshikimate 3-phosphate synthase (EPSPS), also known as 3-phosphoshikimate 1-carboxyvinyltransferase, and UDP-N-acetylglucosamine enolpyruvyl transferase (MurA), also known as UDP-N-acetylglucosamine 1-carboxyvinyltransferase, have both a unique three-dimensional topology and overall reaction mechanism in common
[1]. This entry represents the core domain superfamily of EPSPS and MurA, which transfers enolpryruvate from phosphoenolpyruvate to 3-phosphoshikimate and UDP-N-acetyl-alpha-D-glucosamine respectively.
References
1.Substrate and inhibitor-induced conformational changes in the structurally related enzymes UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS). Krekel F, Oecking C, Amrhein N, Macheroux P. Biochemistry 38, 8864-78, (1999). View articlePMID: 10413459
GO terms
biological process
- None
molecular function
cellular component
- None
Cross References
Contributing Member Database Entry
- CATH-Gene3D:G3DSA:3.65.10.10