5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal
Short name | AMPKA1_C |
Overlapping homologous superfamilies |
Description
References
1.AMP-activated protein kinase: structure and regulation. Sanz P. Curr. Protein Pept. Sci. 9, 478-92, (2008). View articlePMID: 18855699
2.Structural insights into the architecture and allostery of full-length AMP-activated protein kinase. Zhu L, Chen L, Zhou XM, Zhang YY, Zhang YJ, Zhao J, Ji SR, Wu JW, Wu Y. Structure 19, 515-22, (2011). View articlePMID: 21481774
3.LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D. Curr. Biol. 13, 2004-8, (2003). View articlePMID: 14614828
4.Mice lacking AMP-activated protein kinase α1 catalytic subunit have increased bone remodelling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment. Jeyabalan J, Shah M, Viollet B, Roux JP, Chavassieux P, Korbonits M, Chenu C. J. Endocrinol. 214, 349-58, (2012). View articlePMID: 22700192
5.AMPK alpha 1-induced RhoA phosphorylation mediates vasoprotective effect of estradiol. Gayard M, Guilluy C, Rousselle A, Viollet B, Henrion D, Pacaud P, Loirand G, Rolli-Derkinderen M. Arterioscler. Thromb. Vasc. Biol. 31, 2634-42, (2011). View articlePMID: 21852563
6.Muscle-specific deletion of Prkaa1 enhances skeletal muscle lipid accumulation in mice fed a high-fat diet. Wu W, Xu Z, Zhang L, Liu J, Feng J, Wang X, Shan T, Wang Y. J. Physiol. Biochem. (2017). View articlePMID: 29288408
7.The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Shackelford DB, Shaw RJ. Nat. Rev. Cancer 9, 563-75, (2009). View articlePMID: 19629071
8.Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cool B, Zinker B, Chiou W, Kifle L, Cao N, Perham M, Dickinson R, Adler A, Gagne G, Iyengar R, Zhao G, Marsh K, Kym P, Jung P, Camp HS, Frevert E. Cell Metab. 3, 403-16, (2006). View articlePMID: 16753576
GO terms
biological process
- None
molecular function
cellular component
- None
Cross References
Contributing Member Database Entry
- CDD:cd12199